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. 2021 Oct 15;100(41):e27528. doi: 10.1097/MD.0000000000027528

Table 2.

Drugs taken by patients before the onset of late diarrhea and by patients without diarrhea.

Drugs Late diarrhea No diarrhea Diarrhea rate P
No. of different AB
 1 Antibiotic 25 51 32.9% .001
 2 Antibiotics 49 345 12.4% .001
 3 Antibiotics 61 255 19.3% .471
 4 Antibiotics 16 56 22.2% .337
 >4 Antibiotics 8 24 25.0% .300
Individual AB
 Azithromycin 130 622 17.3% .989
 Levofloxacin total 53 206 20.5% <.001
 Levofloxacin oral 35 117 23.0% <.001
 Levofloxacin par. 25 109 18.7% .008
 Moxifloxacin 30 103 22.6% .014
 Moxifloxacin oral 3 19 13.6% .079
 Moxifloxacin par. 27 91 22.9% .037
 Amoxicillin/clavulanic acid 54 210 20.5% .130
 Amoxicillin/clavulanic acid oral 44 136 24.4% .020
 Amoxicillin/clavulanic acid par. 17 95 15.2% .062
 Meropenem 15 46 24.6% .245
 Ceftriaxone 98 523 15.8% .018
 GC 85 245 25.8% .543
 Clarithromycin 13 72 15.3% .179
 Clarithromycin oral 10 28 26.3% .146
 Clarithromycin par. 3 48 5.9% .225
 Josamycin oral 6 12 33.3% .633
 Cefixime oral 3 18 14.3% .328
Antibiotic therapy regimens
 Azithromycin + ceftriaxone 12 146 7.6% .002
Azithromycin + ceftriaxone + GC 9 37 19.6% .784
 Azithromycin + ceftriaxone + other oral AB 14 87 13.9% .246
 Azithromycin + ceftriaxone + GC + other oral AB 13 36 26.5% .112
 Azithromycin + ceftriaxone + other par. AB 7 56 11.1% .138
 Azithromycin + ceftriaxone + other par. AB + GC 10 34 22.7% .408
 Azithromycin + ceftriaxone + other par.AB + other oral AB 5 26 16.1% .777
 Azithromycin + ceftriaxone + other par.AB + other oral AB + GC 10 30 25.0% .242
 Azithromycin + other par. AB 6 40 13.0% .365
 Azithromycin + other par. AB + GC 7 31 18.4% .951
 Azithromycin + other par.AB + other oral AB 3 20 13.0% .527
Azithromycin + other par.AB + other oral AB + GC 12 21 36.4% .005
 Other combinations of oral and par. AB ± GC 13 48 21.3% .286
 Azithromycin only 5 25 16.7% .841
 Оther oral AB ± Azithromycin 16 36 30.8% .014
Any oral AB+GC 8 7 53.3% .003
 Other combinations of par. AB 4 22 15.4% .720
 Other combinations of par. AB +GC 5 29 14.7% .605