Table 2.
Drugs | Late diarrhea | No diarrhea | Diarrhea rate | P |
No. of different AB | ||||
1 Antibiotic | 25 | 51 | 32.9% | .001 |
2 Antibiotics | 49 | 345 | 12.4% | .001 |
3 Antibiotics | 61 | 255 | 19.3% | .471 |
4 Antibiotics | 16 | 56 | 22.2% | .337 |
>4 Antibiotics | 8 | 24 | 25.0% | .300 |
Individual AB | ||||
Azithromycin | 130 | 622 | 17.3% | .989 |
Levofloxacin total | 53 | 206 | 20.5% | <.001 |
Levofloxacin oral | 35 | 117 | 23.0% | <.001 |
Levofloxacin par. | 25 | 109 | 18.7% | .008 |
Moxifloxacin | 30 | 103 | 22.6% | .014 |
Moxifloxacin oral | 3 | 19 | 13.6% | .079 |
Moxifloxacin par. | 27 | 91 | 22.9% | .037 |
Amoxicillin/clavulanic acid | 54 | 210 | 20.5% | .130 |
Amoxicillin/clavulanic acid oral | 44 | 136 | 24.4% | .020 |
Amoxicillin/clavulanic acid par. | 17 | 95 | 15.2% | .062 |
Meropenem | 15 | 46 | 24.6% | .245 |
Ceftriaxone | 98 | 523 | 15.8% | .018 |
GC | 85 | 245 | 25.8% | .543 |
Clarithromycin | 13 | 72 | 15.3% | .179 |
Clarithromycin oral | 10 | 28 | 26.3% | .146 |
Clarithromycin par. | 3 | 48 | 5.9% | .225 |
Josamycin oral | 6 | 12 | 33.3% | .633 |
Cefixime oral | 3 | 18 | 14.3% | .328 |
Antibiotic therapy regimens | ||||
Azithromycin + ceftriaxone | 12 | 146 | 7.6% | .002 |
Azithromycin + ceftriaxone + GC | 9 | 37 | 19.6% | .784 |
Azithromycin + ceftriaxone + other oral AB | 14 | 87 | 13.9% | .246 |
Azithromycin + ceftriaxone + GC + other oral AB | 13 | 36 | 26.5% | .112 |
Azithromycin + ceftriaxone + other par. AB | 7 | 56 | 11.1% | .138 |
Azithromycin + ceftriaxone + other par. AB + GC | 10 | 34 | 22.7% | .408 |
Azithromycin + ceftriaxone + other par.AB + other oral AB | 5 | 26 | 16.1% | .777 |
Azithromycin + ceftriaxone + other par.AB + other oral AB + GC | 10 | 30 | 25.0% | .242 |
Azithromycin + other par. AB | 6 | 40 | 13.0% | .365 |
Azithromycin + other par. AB + GC | 7 | 31 | 18.4% | .951 |
Azithromycin + other par.AB + other oral AB | 3 | 20 | 13.0% | .527 |
Azithromycin + other par.AB + other oral AB + GC | 12 | 21 | 36.4% | .005 |
Other combinations of oral and par. AB ± GC | 13 | 48 | 21.3% | .286 |
Azithromycin only | 5 | 25 | 16.7% | .841 |
Оther oral AB ± Azithromycin | 16 | 36 | 30.8% | .014 |
Any oral AB+GC | 8 | 7 | 53.3% | .003 |
Other combinations of par. AB | 4 | 22 | 15.4% | .720 |
Other combinations of par. AB +GC | 5 | 29 | 14.7% | .605 |