TABLE 1.
Histopathological score of burn wounds in different treatments
| Histological differences seen on H&E-stained sections | Burn alone | Solosite | Low AB569 | High AB569 | PA + high AB569 |
|---|---|---|---|---|---|
| Acute polymorphonuclear leukocyte inflammation (score 0–4 per wound); 0 = no inflammation; 1 = minimal inflammation; 2 = mild; 3 = moderate; 4 = marked inflammation | 4 | 4 | 2 | 3 | 3 |
| Fibroblasts and capillary proliferation (score 0–3 per wound); 0 = no fibroblasts and blood vessels/capillaries; 1 = few fibroblasts with few capillaries; 2 = intermediate presence of fibroblasts and presence of capillaries; 3 = mature fibroblasts and several blood vessels | 1 | 2 | 3 | 2 | 3 |
| Amt of collagen deposition between fibroblasts (score 0–4 per wound); 0 = normal large amt; 1 = marked; 2 = moderate; 3 = mild; 4 = minimal amt | 1 | 1 | 4 | 2 | 1 |
| Total scoring of the wounds (a higher score signifies better healing outcome) | 6 | 7 | 9 | 7 | 7 |