FIG 1.

Infection with H. pylori increased SLFN4⁺ cell percentage and IFN-α expression in mice. Representative by flow cytometry plots (A) showing the percentage of SLFN4⁺ MDSC cells in bone marrow (B), spleen (C), and corpus (D) samples. IFN-α mRNA levels in the gastric corpus determined by qRT-PCR analysis (E) and IFN-α levels in mouse sera determined by ELISA (F) from uninfected (UI) mice and mice infected with H. pylori for 2, 4, or 6 months. *, P < 0.05, **, P < 0.01 versus UI. N = 5 mice/per group.