Table 1.
Demographic and clinical characteristics of patients with OCD and healthy controls
| Characteristic | OCD* (n = 235) | Healthy controls (n = 234) | t or χ2 | p value |
|---|---|---|---|---|
| Age, yr | 27.70 ± 7.55 | 27.23 ± 7.72 | 0.668 | 0.50 |
| Education, high school/college or higher | 126/109 | 123/111 | 0.052 | 0.82 |
| Male/female | 144/91 | 137/97 | 0.364 | 0.55 |
| Body mass index, kg/m2 | 23.07 ± 2.79 | 22.87 ± 3.41 | 0.716 | 0.47 |
| Early Trauma Inventory–Self-Report Short Form score | 6.70 ± 4.77 | 4.19 ± 3.86 | 6.268 | < 0.001 |
| Yale–Brown Obsessive–Compulsive Scale score | 25.79 ± 6.83 | 0.47 ± 1.87 | 54.63 | < 0.001 |
| Montgomery–Åsberg Depression Rating Scale score | 20.54 ± 9.94 | 3.29 ± 3.95 | 24.72 | < 0.001 |
| Age at onset, yr | 18.06 ± 7.30 | — | ||
| Early onset/late onset | 119/116 | — | ||
| Duration of illness, yr | 9.69 ± 6.74 | — | ||
| Cellular aging markers | ||||
| Relative telomere length | 1.042 ± 0.185 | 1.066 ± 0.198 | −1.357 | 0.18 |
| Mitochondrial DNA copy number | 430.12 ± 119.34 | 532.85 ± 113.88 | −9.537 | < 0.001 |
OCD = obsessive–compulsive disorder. Values are mean ± standard deviation or n.
*
Of this group, 77 patients (45 men and 32 women) were drug-naive or had been drug-free for more than 8 weeks.