Table 2.
MANCOVA of leukocyte telomere length and mitochondrial DNA copy number data from male and female OCD and control groups
| Men (n = 281) | Women (n = 188) | |||||
|---|---|---|---|---|---|---|
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| Result | OCD (n = 144) | Healthy controls (n = 137) | p value | OCD (n = 91) | Healthy controls (n = 97) | p value |
| MANCOVA* | Wilks λ = 0.889; F2,275 = 17.13 | < 0.001 | Wilks λ = 0.742; F2,182 = 31.61 | < 0.001 | ||
| Leukocyte telomere length | 1.050 ± 0.185 | 1.043 ± 0.173 | 0.55 | 1.030 ± 0.184 | 1.099 ± 0.225 | 0.023 |
| Mitochondrial DNA copy number | 434.25 ± 116.19 | 519.49 ± 119.48 | < 0.001 | 423.58 ± 124.54 | 551.73 ± 103.14 | < 0.001 |
MANCOVA = multivariate analysis of covariance; OCD = obsessive–compulsive disorder.
*
With age, body mass index and childhood trauma as covariates.