Table 2.
Comparisons of cohorts in recent ophthalmological studies
| End points | Cohorts | ||
|---|---|---|---|
| Atomic bomb survivors | Mayak workers | Radiologic technologists | |
| Countries | Japan | Russia | US |
| Rounded number of eligible study participants | 900–10,000 | 21,000 | 70,000 |
| Male:female | one to 2 | three to 1 | one to 3 |
| Follow-up | ≤60 yearsa | ≤60 yearsb | ≤92 yearsc |
| Mean follow-up | ≤60 yearsa | >30 yearsb | >10 yearsc |
| Medical information | Biennial health exams | Annual health exams | Periodic questionnaire surveysd |
| Exposure scenarios | Acute | Chronic | Protracted |
| Dose evaluated | Eye absorbed dosee | Hp(10)f | Lens absorbed doseg |
| Mean dose | ~0.5 Gye | ~0.5 Svf | ~0.06 Gyg |
| Radiation cataracts in aggregate | Significantly increased | Significantly increased | Significantly increased |
| Radiation posterior subcapsular cataracts | Significantly increased | Significantly increased | N.A. |
| Radiation cortical cataracts | Significantly increased | Significantly increased | N.A. |
| Radiation nuclear cataracts | N.S. | Significantly increased | N.A. |
| Radiation cataract surgery | Significantly increased | N.S. | N.S. |
| Radiation glaucoma in aggregate | Significantly decreased | N.A. | N.S. |
| Radiation primary glaucoma | N.A. | N.S. | N.A. |
| Radiation primary open-angle glaucoma | N.A. | N.S. | N.A. |
| Radiation primary open-angle normal-tention glaucoma | Significantly increased | N.A. | N.A. |
| Radiation primary open-angle high-tention glaucoma | N.S. | N.A. | N.A. |
| Radiation primary angle-closure glaucoma | N.S. | N.A. | N.A. |
| Radiation diabetic retinopathy | Significantly increased | N.A. | N.A. |
| Radiation macular degeneration | N.S. | N.A. | N.S. |
NA, not available; NS, not significant.
Those exposed in 1945 were followed up through 2005.
Those first employed in 1948–1982 were followed up through 2008.
Those certified as radiologic technologists for ≥2 years in 1928–1982 were followed up through 2014.
Self-reporting but by medically literate individuals.
According to the Dosimetry System 2002 (DS02).24
According to the Mayak Worker Dosimetry System 2008 (MWDS–2008).25
According to the updated and improved dosimetry.26