Table 4.
ROC analyses of different parameters to predict mutant P53
| Parameters | Cut-off value | AUC (95% CI) |
Sensitivity (95% CI) |
Specificity (95% CI) |
Accuracy (95% CI) |
|---|---|---|---|---|---|
| CBFuniformity | 0.506 | 0.721 (0.585, 0.857) | 0.606 (0.422, 0.766) | 0.833 (0.618, 0.945) | 0.702 (0.566, 0.816) |
| ETCM | 0.500 | 0.652 (0.572, 0.731) | 0.303 (0.162, 0.489) | 1.000 (0.828, 1.000) | 0.596 (0.458, 0.724) |
| CBFuniformity +ETCM | 0.224 | 0.814 (0.702, 0.927) | 0.758 (0.574, 0.882) | 0.833 (0.618, 0.945) | 0.790 (0.661, 0.886) |
CBFuniformity +ETCM: CBFuniformitycombined with the sign of enhancing tumour crossing midline.AUC, area under the curve; CBF: Cerebral blood flow;CI, confidence interval; ETCM: Enhancing tumour crosses midline.