Table 3.
Association of NRXN-1 mRNA expression in breast cancer cases with different clinicopathological features.
| Variables | NRXN-1 mRNA expression | p value | |
|---|---|---|---|
| Mean | SD | ||
| Relative expression | 11.61 | 7.64 | — |
|
| |||
| Age | |||
| ≤50 years | 8.75 | 7.98 | 0.0003 |
| >50 years | 14.98 | 8.71 | |
|
| |||
| Menopause | |||
| Yes | 13.01 | 8.86 | 0.03 |
| No | 8.78 | 8.23 | |
|
| |||
| Lymph nodes involvement | |||
| Yes | 15.70 | 8.96 | <0.0001 |
| No | 8.40 | 7.37 | |
|
| |||
| ER status | |||
| Positive | 14.05 | 7.83 | 0.03 |
| Negative | 10.52 | 9.11 | |
|
| |||
| PR status | |||
| Positive | 15.29 | 7.43 | 0.005 |
| Negative | 10.18 | 8.98 | |
|
| |||
| HER2 status | |||
| Positive | 12.71 | 8.36 | 0.20 |
| Negative | 10.88 | 9.15 | |
|
| |||
| TNM stages | |||
| Early stage (I & II) | 3.18 | 1.04 | <0.0001 |
| Advanced stage (III & IV) | 16.78 | 7.41 | |
|
| |||
| Distant metastases | |||
| Yes | 18.72 | 8.28 | <0.0001 |
| No | 9.37 | 7.81 | |