Table 6.

ROC curve for microRNA-495, NRXN-1, and CNTN-1 w.r.t. metastases (no metastases and distant organ metastases).

AUC for microRNA-21 (95% CI)	Sensitivity	Specificity	Cutoff value (fold change)	p value
0.57 (0.46–0.68)	57%	46%	0.04-fold	0.27
AUC for NRXN-1 (95% CI)	Sensitivity	Specificity	Cutoff value (fold change)	p value
0.79 (0.70–0.88)	70%	66%	13.36-fold	<0.0001
AUC for CNTN-1 (95% CI)	Sensitivity	Specificity	Cutoff value (fold change)	p value
0.86 (0.78–0.93)	75%	74%	5.7-fold	<0.0001