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. 2021 Oct 16;158:106930. doi: 10.1016/j.envint.2021.106930

Table 2.

Demography, anthropometry, clinical characteristics and long-term exposure to environmental pollutants of the population according to COVID-19 severity

Mild Severe Death p.overall
N 1417 344 351 <0.001
Age 64.0
[52.0;77.0]
62.0 [53.0;71.0] 80.0
[73.0;87.0]
<0.001
Sex (female) 646 (45.6%) 117 (34.0%) 143 (40.7%) <0.001
Smoker 64 (4.83%) 23 (7.06%) 18 (5.39%)
Personal history of diseases
High Blood Pressure 649 (45.9%) 156 (45.5%) 248 (70.7%) <0.001
Diabetes 296 (20.9%) 84 (24.4%) 114 (32.5%) <0.001
Obesity 320 (26.9%) 108 (36.4%) 90 (29.6%) 0.005
Coronary Heart Disease 120 (8.47%) 29 (8.43%) 47 (13.4%) 0.014
Stroke 78 (5.50%) 18 (5.23%) 36 (10.3%) 0.003
Peripheral Arterial Disease 51 (3.60%) 15 (4.36%) 33 (9.40%) <0.001
Heart Failure 98 (6.92%) 14 (4.07%) 67 (19.1%) <0.001
COPD/Asthma 212 (15.0%) 59 (17.2%) 90 (25.6%) <0.001
Chronic Liver disease 37 (2.61%) 7 (2.03%) 14 (3.99%) 0.250
Chronic Kidney disease 118 (8.33%) 20 (5.81%) 73 (20.8%) <0.001
Rheumatologic disease 64 (4.52%) 19 (5.52%) 20 (5.70%) 0.549
Cancer 137 (9.68%) 37 (10.8%) 64 (18.2%) <0.001
Clinical outcomes
Intensive Care Unit Hospitalization 11 (0.78%) 230 (67.1%) 81 (23.1%) <0.001
Fever 1152 (81.5%) 313 (91.0%) 296 (84.8%) <0.001
Cough 946 (67.3%) 277 (81.2%) 224 (65.5%) <0.001
Dyspnea 707 (50.1%) 283 (82.3%) 248 (71.3%) <0.001
Bilateral alteration Thorax X ray 949 (67.3%) 317 (92.2%) 295 (84.5%) <0.001
Acute Respiratory Distress Syndrome 96 (6.79%) 257 (74.9%) 257 (73.6%) <0.001
Respiratory Failure 215 (20.9%) 141 (43.3%) 150 (54.7%) <0.001
High-Flow Mechanical Ventilation 26 (1.84%) 224 (65.1%) 120 (34.2%) <0.001
Invasive Mechanical Ventilation. Tracheal Intubation 1 (0.07%) 188 (54.7%) 73 (20.8%) <0.001
Disseminated Intravascular Coagulation 5 (0.35%) 13 (3.80%) 18 (5.16%) <0.001
Acute Renale Failure 119 (8.42%) 78 (22.7%) 144 (41.1%) <0.001
Liver alterations 19 (1.35%) 23 (6.69%) 25 (7.14%) <0.001
Shock 3 (0.21%) 55 (16.0%) 74 (21.2%) <0.001
Long-term exposure to environmental pollutants
NO2 (µg/m3) 30.2 30.2 30.2
PM10 (µg/m3) 24.0 24.0 24.0