TABLE 4.

Summary of mTBI studies using SWI

Author	Participants, acute vs. chronic phase	Major findings
Park et al. (2009)	21 mTBI patients without any parenchymal hemorrhage on conventional MRI, within a week after admission	Microbleeds were located more frequently in white matter than in deep nucleus. Lesions were observed in the frontal lobe, occipital lobe, and brain stem.
Hasiloglu et al. (2011)	21 amateur boxers	Microhemorrhages were detected only in 2 of 10 patients.
Wang et al. (2014)	200 mTBI patients, 2 hr to 3 days postinjury, with follow‐up testing (on presence of depressive symptoms) 1 year after	Depressive group had greater the number and volume of microbleeds than nondepressive group, particularly in the frontal, parietal, and temporal lobes.
Liu et al. (2013)	63 MTBI patients at least 3 days after injury, and follow‐up testing on PCS after 7–15 months	Significant correlation was found between PCS and number of intracranial microbleeds.
Lu et al. (2015)	39 patients with mTBI, 6 months after injury	Significantly higher angle radian values were observed in the head of the caudate nucleus, the lenticular nucleus, the hippocampus, the thalamus, the right substantia nigra, the red nucleus, and the splenium of the CC.
De Haan, de Groot, Jacobs, and van der Naalt (2017)	127 individuals with mTBI (63 with MRI abnormalities and 64 without), chronic phase	Microhemorrhages were predominantly present in the frontal and temporal lobes. Worse outcome was demonstrated in 67% of the group with MRI abnormalities with a significant association of the total number of microhemorrhages in the temporal cortical area.
Trifan, Gattu, Haacke, Kou, and Benson (2017)	180 subjects with persistent neurobehavioral symptoms following head trauma (83% classified as mTBI), chronic phase (~29 months postinjury)	28% of the 180 TBI cases revealed hemorrhages.
Studerus‐Germann et al. (2018)	30 mTBI patients tested at the baseline and 12 months postinjury	Amount of microbleeds in the acute phase correlates positively with cognitive symptoms such as slowing, difficulty in memory and concentration.
Einarsen et al. (2019)	194 mTBI patients, 72 hr, 3 months, and 12 months postinjury	TAI lesions in the lobar WM, CC, brainstem, basal ganglia, and thalamus, in 19% of participants after 3 months and in 16% after 12 months.