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. 2021 Oct 15;12:6023. doi: 10.1038/s41467-021-26299-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a The performance of pathway-based super signature (PASS-PRE) and time-response interaction pathway-based super signatures for pre-treatment samples (TimeANLS-PRE) in comparison with publicly existing signatures. b The performance of pathway-based super signature (PASS-ON) and time-response interaction pathway-based super signatures for on-treatment samples (TimeANLS-ON) with existing signatures. Each cohort’s sample number were showed in the legend. The mean value and standard deviation of AUCs were showed as error bar. Source data are provided as a Source Data file.