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. 2021 Oct 15;4(10):e2129409. doi: 10.1001/jamanetworkopen.2021.29409

Table 1. Differences in Main Motivation Between the Most Recent Buprenorphine Misuse and Nonbuprenorphine Prescription Opioid Misuse by Past-Year Buprenorphine Misuse and OUD Status.

Main motivation for misuse OUD status, weighted % (95% CI)a
OUD No OUD
Nonbuprenorphine prescription misuse (n = 1382) Buprenorphine misuse (n = 233) Nonbuprenorphine prescription misuse (n = 7898) Buprenorphine misuse (n = 213)
Relieve physical pain 52.2 (47.6-56.8)b 20.5 (14.0-29.0)b,c 66.6 (65.0-68.2)c 29.3 (21.2-39.1)b,c
Relax or relieve tension 8.9 (7.0-11.1) 3.7 (1.6-8.3)b,c 10.5 (9.4-11.7) 6.8 (3.2-14.0)
Experiment 1.4 (0.7-2.7) 1.6 (0.5-5.4) 2.4 (2.1-2.8) 8.5 (4.9-14.3)b,c
Feel good or get high 17.1 (14.4-20.2)b 9.4 (5.9-14.6)c 10.3 (9.4-11.3)c 18.1 (11.5-27.4)b
Help with my feelings or emotions 6.3 (4.8-8.2)b 8.2 (3.4-18.6)b,d 2.6 (2.1-3.2)c 11.7 (5.8-22.2)b,d
Increase/decrease effect(s) of other drugs 1.2 (0.3-4.4)d 15.1 (9.5-23.1)b,c 0.5 (0.3-0.8) 3.6 (2.2-5.9)b
Because I am hooked 7.8 (6.2-9.9)b 27.3 (21.6-33.8)b,c 0.2 (0.1-0.3)c 12.7 (7.3-21.2)b

Abbreviation: OUD, opioid use disorder.

a

Data are from 9726 respondents in the 2015-2019 National Surveys on Drug Use and Health.

b

This estimate is statistically significantly (P < .05) different from the estimate of the corresponding adults with nonbuprenorphine prescription opioid misuse but no OUD (within each row).

c

This estimate is statistically significantly (P < .05) different from the estimate of the corresponding adults with nonbuprenorphine opioid misuse and with OUD (within each row).

d

Interpret with caution owing to low statistical precision.