Figure 3. (A) Pre-treatment biopsies revealing finger-like projections (white arrow) with hyperplasia of stratum spinosum of epidermis and hyperkeratosis supported by fibroblastic proliferation of connective tissue core. Presence of koilocytes (keratinocytes within the stratum spinosum with a clear perinuclear halo) (black arrow). (B) Multiple papillomas showing islands of epithelial cells surrounded by lamellar keratin (H&E stain).