Table 5. Influence of the ethanolic extract of P. americana seed flour on oxidative stress markers in the uterus of guinea pigs.
| Oxidative stress markers | Control (n = 6) | Doses of ethanolic extract of P. americana seed flour (mg/kg bw) | p-value | ||
|---|---|---|---|---|---|
| EE100 (n = 6) | EE200 (n = 6) | EE400 (n = 6) | |||
| Total proteins (gm/dl) | 1.74 ± 0.18 | 1.58 ± 0.10 | 1.79 ± 0.38 | 1.57 ± 0.25 | 0.36 |
| MDA (μM) | 1.27 ± 0.59 | 1.06 ± 0.30 | 0.91 ± 0.17 | 1.02 ± 0.12 | 0.36 |
| SOD U/min/gm of uterine proteins) | 0.77 ± 0.09b | 0.91 ± 0.03a | 0.93 ± 0.07a | 0.91 ± 0.05a | 0.00 |
| CAT (μM/min/gm of uterine proteins) | 1.23 ± 0.21 | 1.34 ± 0.11 | 1.17 ± 0.18 | 1.35 ± 0.13 | 0.20 |
| POX (mM/min/gm of uterine proteins) | 24.89 ± 9.69 | 22.57 ± 5.78 | 22.65 ± 8.08 | 21.86 ± 2.99 | 0.89 |
means with different letters are significantly different (p < 0.05). n = number of samples; p = probability; Control = 1 ml/kg bw of distilled water; EE100, EE200, and EE400 = ethanol extract of P. americana seed flour at 100, 200, and 400 mg/kg bw, respectively. MDA = malondialdehyde; SOD = superoxide dismutase; CAT = catalase; POX = total peroxidase.