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. 2021 Sep 20;8(3):501–510. doi: 10.5455/javar.2021.h540

Table 5. Influence of the ethanolic extract of P. americana seed flour on oxidative stress markers in the uterus of guinea pigs.

Oxidative stress markers Control (n = 6) Doses of ethanolic extract of P. americana seed flour (mg/kg bw) p-value
EE100 (n = 6) EE200 (n = 6) EE400 (n = 6)
Total proteins (gm/dl) 1.74 ± 0.18 1.58 ± 0.10 1.79 ± 0.38 1.57 ± 0.25 0.36
MDA (μM) 1.27 ± 0.59 1.06 ± 0.30 0.91 ± 0.17 1.02 ± 0.12 0.36
SOD U/min/gm of uterine proteins) 0.77 ± 0.09b 0.91 ± 0.03a 0.93 ± 0.07a 0.91 ± 0.05a 0.00
CAT (μM/min/gm of uterine proteins) 1.23 ± 0.21 1.34 ± 0.11 1.17 ± 0.18 1.35 ± 0.13 0.20
POX (mM/min/gm of uterine proteins) 24.89 ± 9.69 22.57 ± 5.78 22.65 ± 8.08 21.86 ± 2.99 0.89
(a, b)

means with different letters are significantly different (p < 0.05). n = number of samples; p = probability; Control = 1 ml/kg bw of distilled water; EE100, EE200, and EE400 = ethanol extract of P. americana seed flour at 100, 200, and 400 mg/kg bw, respectively. MDA = malondialdehyde; SOD = superoxide dismutase; CAT = catalase; POX = total peroxidase.