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. 2021 Oct 16;161(4):979–988. doi: 10.1016/j.chest.2021.10.012

Table 2.

Lung Tissue and Gas Distribution With 5 and 45 cm H2O of Airway Pressure

Variable Quantitative Analysis of Lung CT P
Airway pressure, cm H2O 5 45
No. 20 20
Total lung
 Tissue, g 1,336 (1,112-1,586) 1,439 (1,157-1,575) .062
 Gas, mL 950 (577-1,230) 2,905 (2,410-3,345) < .001
Non-aerated
 Tissue, g 555 (404-742) 197 (115-307) < .001
 Gas, mL 3 (0-10) 0 (0-2) .008
Poorly aerated
 Tissue, g 502 (364-601) 378 (313-498) .011
 Gas, mL 192 (160-256) 199 (164-274) .852
Normally aerated
 Tissue, g 255 (156-382) 777 (598-882) < .001
 Gas, mL 658 (356-922) 2,288 (1,474-2,484) < .001
Over-aerated
 Tissue, g 3 (0-7) 31 (18-45) < .001
 Gas, mL 46 (6-131) 476 (217-766) < .001

Twenty patients underwent a lung CT at 5 and 45 cm H2O of airway pressure. Herein we compare the distribution of tissue and gas in their whole lungs and in their four compartments at these two airway pressures. Data are reported as median (Q1-Q3). P value refers to the Wilcoxon signed rank-sum test. If the nonaerated compartment had a density > 0 HU (ie, higher than the density of water), the gas volume was considered zero.