Table 2.

Previously reported cases of subacute thyroiditis after vaccination against COVID-19.

	Case 1 [9]	Case 2 [9]	Case 3 [9]	Case 4 [11]	Case 5 [10]	Case 6 [8]	Case 7 [13]	Case 8 [7]	Case 9 [12]	Case 10 [12]
Age	35	34	37	67	57	42	55	75	26	49
Sex	Female	Female	Female	Male	Female	Female	Female	Male	Female	Female
Type of vaccine	CoronaVac®	CoronaVac®	CoronaVac®	CoronaVac®	BNT162B2	BNT162B2	ChAdOx1-S	ChAdOx1-S	ChAdOx1-S	Spikevax
Time of symptoms onset	4 days after 1st dose	4 days after 1st dose	7 days after 2nd dose	17 days after 2nd dose	1 day after 2nd dose	5 days after 2nd dose	21 days after 1st dose	14 days after 1st dose	2 days after 1st dose	7 days after 1st dose
Symptoms	Neck pain, palpiyations	Neck pain, fatigue, weight loss	Neck pain	Fever, weight loss, mild neck pain	Neck pain and swelling	Sore throat, palpitations	Neck pain and swelling, sore throat, headache, palpitations	Neck pain and tenderness, shortness of breath, intermittent palpitations, insomnia and generalized anxiety	Fever, neck pain	Sore throat, headaches and difficulty in concentrating
Thyroid function testsa	↓TSH, ↑fT3	↓TSH, ↓fT4 ↑fT3	↓TSH, ↑fT3	↓TSH, ↑fT4, ↑fT3	↓TSH, ↑fT4	↓TSH	↓TSH, ↑fT4	↓TSH, ↑fT4, ↑fT3	↑fT3	Euthyroid
TPOAb	Negative	Negative	Negative	Negative	Negative	Negative	Negative	Negative	Negative	Negative
TGAb	Negative	Negative	Negative	Negative	Negative	Negative	NA	Negative	Negative	Negative
TRAbs	Negative	Negative	Negative	Negative	Negative	Negative	Negative	Negative	Negative	Negative
Thyroid scintigraphy	NA	NA	NA	NA	NA	NA	NA	↓ uptake	NA	NA
Nasopharyngeal swab testing for SARS-CoV-2	Negative	Negative	Negative	Negative	Negative	Negative	Negative	NA	NA	NA
Antibodies to the spike protein of SARS-CoV-2	NA	NA	NA	NA	NA	NA	NA	↑↑	NA	NA
Outcome in reassessment	Euthyroidism	Thyrotoxicosis	Thyrotoxicosis	Euthyroidism	NA	Thyrotoxicosis	Hypothyroidism	Euthyroidism	Euthyroidism	Euthyroidism

Abbrevations: TGAb, anti-thyroglobulin antibody; TPOAb, thyroid peroxidise antibody; fT3, free triiodothyronine; fT4, free thyroxine; NA, not assessed; TRAB, TSH receptor antibodies; TSH, thyroid-stimulating hormone.

^aOnly abnormal laboratory results are noted.