Weight gain of +/+, tub/tub, and −/− mice: (A) Weight gain of male wild-type (+/+), tubby (tub/tub), and tub-deficient (−/−) mice. The weights of 10 mice of each genotype were measured at the indicated times. (B) Weight gain of female wild-type, tubby, and tub-deficient mice. The weights of 10 mice of each genotype were measured at the indicated times.