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. 2021 Oct 12;13:1823–1863. doi: 10.2147/NSS.S332474

Table 1.

Common TCM Syndrome Patterns of PMI and PMD

Syndrome Patterns Major Symptoms Tongue Pulse Ratio
PMI PMD
Depression of liver and deficiency of kidney Insomnia or dreamful sleep, depressed mood, fatigue, chest distress and preference for sighing, hot flushes and sweating, frequent urination or dribbling urination Red tongue with little coating Stringy and thready, or stringy and rapid 60.78% 30.42%
Liver depression and spleen deficiency Depression or irritability, poor sleep, poor appetite, abdominal distension, loose stool White coated tongue Stringy and slow 24.02%
Stagnation of Qi due to depression of liver Depression or irritability, preference for sighing, hypochondrium distress and/or pain, distending pain of breasts Thin whitish coating of the tongue Stringy 18.80%
Imbalance between heart-Yang and kidney-Yin Irritability and insomnia, palpitation, dizziness and tinnitus, loss of memory, dry mouth, soreness and weakness of waist and knees Red tongue with little coating Thready and rapid 13.46%
Spleen–kidney Yang deficiency Insomnia due to nocturia, soreness and weakness of waist and knees, chilly sensation and the cold limbs, diarrhea before dawn or loose stools, edema in the extremities Pale and slight corpulent tongue with whitish and slippery fur Deep and retarded without strength 4.31%
Deficiency of both kidney Yin and kidney Yang Poor sleep, sometimes hot flushes and sweating and sometimes chilly sensation and the cold limbs, soreness and weakness of waist and knees, dizziness and tinnitus Pale tongue with thin coating Stringy and thready 4.31%
Heart-Gallbladder Qi deficiency Palpitation, timidity, feeling fearful, difficulty in falling asleep, tendency to sleep lightly, nightmares, depressed mood, short of breath, spontaneous perspiration Pale tongue with whitish coating Stringy and thready 3.70% 6.72%
Heart–spleen deficiency Insomnia, dreamful sleep, worry beyond measure, palpitation, poor appetite, loose stool, fatigue, sallow complexion, loss of memory Pale tongue with whitish coating Thin and weak 2.87% 6.11%
Hyperactivity of fire due to Yin deficiency Vexation, irritable and depressed mood, dry mouth, tidal reddening of the cheeks, dysphoria in chest palms-soles Red tongue with little coating Stringy and rapid 4.65%

Table 1 is not a direct quote from any paper, but is compiled by us from data in two published papers (Ref 47 & 48 of this manuscript); Similarly, Table 3 is compiled by us from data in two published papers (Ref 19 & 50 of this manuscript); The rest of the tables and figures are original and do not require reference. 47 and 48.