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. 2021 Oct 16;11(10):167. doi: 10.1038/s41408-021-00561-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Morphologic features of ZBTB16-RARA variant and flow cytometry characteristics of AML with RARA variants and PML-RARA-positive APL. The majority of blasts have hypergranular cytoplasm; in a minority of cases, Auer rods were present (UPN10 and UPN18). The majority of blasts harbored a regular round or oval nucleus that was more suggestive of FAB type M2; however, a minority of blasts in UPN 11 and UPN 18 showed irregular and indented nuclei. B Survival outcome of patients with RARA variant translocations.