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. 2021 Oct 18;9:54. doi: 10.1186/s40635-021-00419-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — ABBU breath triggering data. A Representative pressure–time scalar (blue) during one porcine experiment. The first five breaths are trigger assisted (blue arrows), followed by a two respiratory cycle pause (green arrow), followed by three control breaths (orange arrows). Mode = Breath means a mechanical breath is being is delivered, Mode = Home means the motor is idle and Paw is below PEEP, Mode = Search is when it calculates PEEP and is searching for a patient effort, and Mode = Trigger means a breath assist is triggered. B Summary of trigger assist algorithm (n = 2). Note that Subject #6 had 22 false negatives (ineffective triggering) attributed to inability of the algorithm to calculate the sensing threshold below PEEP during periods of rapid breathing (50–60 bpm)