Table 4.
Cox regression analysis progression free survival
| Variables | Univariable | Multivariable | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Sarcopenia | 1.84 (1.11–3.06) | 0.019 | 1.66 (0.98–2.83) | 0.061 |
| Age at diagnosis a/mSTS | 1.02 (1.00–1.04) | 0.049 | 1.01 (0.99–1.03) | 0.156 |
| Gender | 1.28 (0.80–2.07) | 0.307 | ||
| Tumor characteristics, at initial diagnosis | ||||
| Site (superficial/deep) | 0.78 (0.30–2.04) | 0.611 | ||
| Size (≤ 5 cm/ > 5 cm) | 0.93 (0.53–1.65) | 0.811 | ||
| Grade (G1/G2 + 3) | 1.17 (0.70–1.95) | 0.553 | ||
| Resection status (R0/Other) | 1.34 (0.76–2.39) | 0.315 | ||
| Histologic subtype | ||||
| Leiomyosarcoma | 1 (df = 3) | 0.980 | ||
| Liposarcoma | 0.86 (0.36–2.04) | 0.725 | ||
| Sarcoma NOS | 0.97 (0.53–1.79) | 0.922 | ||
| Other | 0.90 (0.48–1.70) | 0.750 | ||
| Metastasis at diagnosis a/mSTS (no/yes) | ||||
| Lung metastases | 0.87 (0.53–1.42) | 0.565 | ||
| Liver metastases | 1.04 (0.62–1.76) | 0.879 | ||
| Lymph node metastases | 1.31 (0.76–2.28) | 0.331 | ||
| Soft tissue metastases | 1.09 (0.65–1.84) | 0.742 | ||
| Cerebral metastases | 1.88 (0.26–13.77) | 0.534 | ||
| Bone metastases | 1.25 (0.69–2.28) | 0.467 | ||
| Primary site recurrence | 1.28 (.76–2.16) | 0.357 | ||
| Other | 1.05 (.62–1.77) | 0.863 | ||
| No. organs w/metastasis (1/ > 1) | 1.37 (0.85–2.22) | 0.196 | 1.35 | 0.217 |
| Mode of metastatic spread (synchronous/metachronous) | 0.89 (0.55–1.45) | 0.892 | ||
| MT + (CTx + Sx/RTx), vs. MT – (CTx only) | 0.76 (0.47–1.24) | 0.274 | ||
| ECOG at diagnosis a/mSTS (0 / ≥ 1) | 1.11 (0.68–1.81) | 0.679 | ||