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. 2021 Oct 13;14:5241–5249. doi: 10.2147/JIR.S329921

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© 2021 Lai et al.

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Phorbol 12-myristate 13-acetate (PMA) treatment causes cell growth inhibition and cytotoxicity in THP-1-differentiated macrophages. According to the experimental design shown in Figure 1A, (A) MTT and (B) lactate dehydrogenase (LDH)/MTT assays showed cell growth and cytotoxicity, respectively, in PMA-treated THP-1 cells. The original optical density (O.D.) of MTT and the ratio of LDH/MTT were shown. All quantitative data are shown as the mean ± SD of three independent experiments. ***p < 0.001.