Table 1.
Values of the hemodynamic parameters in the non-preconditioned and preconditioned hearts are measured at the different phases of preischemia and postischemia.
| Preischemic | Endischemia | Reperfusion time | |||||
|---|---|---|---|---|---|---|---|
| 2 min | 15 min | 30 min | 60 min | 90 min | |||
| HR | |||||||
| Control | 218.53 ± 4.3 | 210.1 ± 7.5 | 214.46 ± 8.9a | 214.96 ± 8.3 | 211.66 ± 10.1 | 201.5 ± 11.4 | 197.73 ± 14.2 |
| Ischemia/Reperfusion(I/R) | 243.96 ± 10.6 | 0a | 242 ± 12.6 | 238.3 ± 11.7 | 230.33 ± 15.8 | 212.33 ± 6.4 | 212.66 ± 5.5 |
| Sham | 242.93 ± 12.1 | 0a | 242.8 ± 18.6 | 222.02 ± 14.5 | 216.86 ± 18.2 | 216.93 ± 6.7 | 205.09 ± 5.67 |
| Treatment | 251.5 ± 6.6 | 0a | 266.64 ± 17.84a | 238.06 ± 17 | 244.73 ± 10.9 | 234.9 ± 8.1 | 230.73 ± 12.1 |
| LVDP | |||||||
| Control | 89.1 ± 4.2 | 90.35 ± 7.1 | 89.19 ± 5.3 | 79.09 ± 9 | 86.68 ± 7 | 84.38 ± 7 | 82.85 ± 7.1 |
| Ischemia/Reperfusion(I/R) | 94.32 ± 1 | 0a | 69.78 ± 3.7a | 75.12 ± 5.9 | 76.41 ± 3.9 | 70.66 ± 2.7 | 65.26 ± 0.4a |
| Sham | 78.12 ± 5.1 | 0a | 64.27 ± 8.4a | 56.13 ± 5a,b | 58.14 ± 7.5a,b | 53.9 ± 8.9a | 49.75 ± 7a |
| Treatment | 91.75 ± 2.8 | 0a | 86.79 ± 2.6 | 96.18 ± 5.7b,c | 97.04 ± 1.9b,c | 93.19 ± 2.5b,c | 90.15 ± 4.4b,c |
Data are expressed as means ± SE. Obtained from at least six tested mice in each group.
HR, heart rate (beats/min); I/R, ischemia/reperfusion; LVDP, left ventricular developed pressure (LV systolic minus LV diastolic pressure, mmHg).
a
p < 0.05 vs. control.
b
p < 0.05 vs. I/R.
c
p < 0.05 vs. sham-operated.