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. 2021 Oct 4;12:750397. doi: 10.3389/fphar.2021.750397

FIGURE 2.

FIGURE 2

Social interaction with relapsed partners for over 30 min triggered relapse to drug-seeking behavior and this effect lasted for at least 1 day. (A) Experimental timeline. (B) Active nosepokes were enhanced after social interaction with relapsed partner for 30 or 60 min. (C) Inactive nosepokes had no change after social interaction (Data are shown as mean ± SEM. *p < 0.05, compared with extinction test. n = 7–9). (D) Active nosepokes were increased immediately or 1 day after 30 min social interaction with relapsed partner. (E) Inactive nosepokes had no change after social interaction (Data are shown as mean ± SEM. *p < 0.05, compared with extinction test. n = 6–9).