Table 1.
The Influence of HA Fillers (HA-Y and HA-S) on the Area of Signaling Molecules Expression in Mixed Culture of Keratinocytes and Fibroblasts
| Marker | Group | Area of Expression (%) | |
|---|---|---|---|
| Passage 3 (Mean±SD) | Passage 6 (Mean±SD) | ||
| AP-1 | Control | 15.54±1.18 | 21.86±1.82 |
| HA-Y | 16.02±1.45 | 16.94±1.32 | |
| HA-S | 15.86±1.12 | 16.52±1.04 | |
| Klotho | Control | 1.12±0.16 | 1.36±0.09 |
| HA-Y | 1.34±0.08 | 5.05±0.37 | |
| HA-S | 1.47±0.12 | 4.98±0.41 | |
| Clock | Control | 11.41±1.13 | 7.25±0.83 |
| HA-Y | 13.43±0.98 | 9.24±1.19 | |
| HA-S | 15.28±1.21 | 10.78±1.07 | |
| Elastin | Control | 48.63±4.54 | 26.05±3.62 |
| HA-Y | 57.32±3.91 | 35.8±3.7 | |
| HA-S | 55.39±4.65 | 39.51±3.58 | |
| MTH-1 | Control | 20.74±2.4 | 14.53±2.81 |
| HA-Y | 21.28±2.72 | 19.87±2.69 | |
| HA-S | 22.06±2.92 | 19.43±2.66 | |