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Progressive FBB retention in the brains of ARTE10 and APP/PS mice. Wild-type control animals, homozygous ARTE10 mice at the age of 9, 15, or 21 months, and 24-month-old APPswe/PS1ΔE9 (APP/PS) were subjected to FBB PET. Coronal (left) and sagittal (right) views of cranial tracer retention (% injected dose per volume, %ID/mL) averaged over 25–90 min post-injection. Representative animals are shown coregistered to a mouse brain MRI atlas.
