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Quantification of amyloid plaque pathology in the brains of ARTE10 and APPswe/PS1ΔE9 mice. Plaque load (A), number (B), and average size (C) of amyloid plaques were quantified on Congo red–stained sagittal brain slices from 24-month-old APPswe/PS1ΔE9 (APP/PS) and ARTE10 mice of different ages (9–21 months). Data are expressed as mean ± SEM; ns, not significant, *p < 0.05, **p < 0.001, ***p < 0.0001 vs. APP/PS.
