TABLE 1.
Mouse model | Mean age ± SD (months) | Body weight mean ± SD (g) | Total no. (m + f) | PET | Ex vivo autoradiography | Plaque analysis |
ARTE10 9 months | 9.1 ± 0.4 | 25.3 ± 4.5 | 8 (4 + 4) | 6 (3 + 3) | 6 (3 + 3) | 8 (4 + 4) |
ARTE10 15 months | 15.1 ± 0.1 | 24.6 ± 4.3 | 9 (5 + 4) | 7 (3 + 4) | 6 (2 + 4) | 8 (4 + 4) |
ARTE10 21 months | 21.4 ± 0.6 | 27.0 ± 3.6 | 7 (4 + 3) | 7 (4 + 3) | 7 (4 + 3) | 7 (4 + 3) |
APPswe/PS1ΔE9 | 24.1 ± 0.4 | 26.9 ± 4.7 | 10 (5 + 5) | 9 (4 + 5) | NA | 7 (5 + 2) |
Wild-type | 24.2 ± 0.6 | 29.8 ± 2.9 | 9 (5 + 4) | 9 (5 + 4) | 8 (4 + 4) | NA |
F, female; m, male; NA, not analyzed.