TABLE 4.
Parameter | RTK (mean ± SD) | Non-RTK (mean ± SD) | FDR-adjusted p-value |
OEF (%) | 22.021 ± 4.191 | 18.191 ± 3.635 | 0.003 † |
Ktrans (mL/min) | 0.058 ± 0.037 | 0.047 ± 0.031 | 0.137‡ |
CBV (mL/100 g) | 3.003 ± 2.562 | 1.563 ± 0.816 | 0.004 ‡ |
CBF (mL/100 g per min) | 201.754 ± 104.509 | 140.769 ± 56.485 | 0.011 ‡ |
OEF, oxygen extraction fraction; Ktrans, volume transfer constant; CBV, cerebral blood volume; CBF, cerebral blood flow; RTK, receptor tyrosine kinase.
p-values were calculated using Student t-test† or Wilcoxon rank-sum test‡ with false FDR correction (<0.05). Statistically significant p-values are highlighted in bold.