TABLE 5.
Comparison of biomarkers for WHO tumor grades.
| Parameter | LGG (mean ± SD) | GBM (mean ± SD) | FDR-adjusted p-value |
| OEF (%) | 18.48 ± 4.85 | 24.17 ± 4.86 | <0.0001 ‡ |
| Ktrans (mL/min) | 0.04 ± 0.02 | 0.09 ± 0.05 | <0.0001 ‡ |
| CBV (mL/100 g) | 2.11 ± 1.55 | 5.07 ± 4.17 | <0.0001 ‡ |
| CBF (mL/100 g per min) | 164.80 ± 101.10 | 314.10 ± 172.00 | <0.0001 ‡ |
OEF, oxygen extraction fraction; Ktrans, volume transfer constant; CBV, cerebral blood volume; CBF, cerebral blood flow; LGG, lower-grade glioma; GBM, glioblastoma.
p-values were calculated using Wilcoxon rank-sum test‡ with false discovery rate (FDR) correction (<0.05). Statistically significant p-values are highlighted in bold.