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The causal effect estimates of hypothyroidism on PBC (A) as well as the causal effect estimates of PBC on hypothyroidism (B) from multiple Mendelian randomization methods with different model assumptions. IVW, inverse variance weighted method; MR, Mendelian randomization; MRPRESSO, Mendelian randomization pleiotropy residual sum and outlier; MR-RAPS, Mendelian randomization robust adjusted profile score; PBC, primary biliary cirrhosis.
