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. 2021 Oct 4;9:741058. doi: 10.3389/fchem.2021.741058

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Copyright © 2021 Yin, Wan, Qian, Sohan, Wang and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Design and assembly of an integrated SMC with the PM valve for the chemiluminescence immunoassay. (A) Schematic diagram of the top microchannel layer with embedded microchannels, the middle reaction layer with patterned antibody stripes, the base layer, and the PM valve before assembly. (B) Schematic diagram of the integrated chip and the operation manual of the PM valve. The inset figure is the enlargement of the side view for the PM valve connected to the reservoirs and nine reaction spots on the silicon film. (C) Picture of the SMC mold and PM valve. (D) Image of the assembled SMC.