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. 2021 Oct 4;12:722258. doi: 10.3389/fphar.2021.722258

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Copyright © 2021 Subash-Babu, Al-Saran, M. Alshammari, Naif Al-Harbi, Hussain Alhussain, Shamlan, Abdulaziz AlSedairy and Abdullah Alshatwi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vitro cytotoxicity (6A), microtubule development (6B), PI and JC-1 (6C) stained microscopic image analysis of vehicle control, BSE, CSE, and BSE-SLNp treated H₂O₂ induced oxidative stressed HUVECs after 48 h. Each value is means ± SD (n = 6). In PI staining, the nucleus appeared to be normal and there are no signs of shrunken, pyknosis, or apoptotic nucleus. BSE-SLNp treated adipocyte showing high J-aggregates directly representing active mitochondria (high MMP, Δψ_m).