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. 2021 Oct 4;15:726505. doi: 10.3389/fnins.2021.726505

TABLE 4.

Clinical outcome measures in each group.

TA (n = 24) SA (n = 20) p b p c

Outcome Measure Mean ± SD Mean ± SD
SAS
 Baseline 49.95 ± 10.82 49.96 ± 10.72 0.998 pT = 0.000
 4 weeks 45.29 ± 7.97 46.68 ± 11.92 0.639 pT*G = 0.641
 8 weeks 42.52 ± 6.94 45.64 ± 10.19 0.639 pG = 0.521
 12 weeks 42.81 ± 8.28 45.16 ± 12.28 0.460
 pa <0.001 0.016
SDS
 Baseline 51.19 ± 12.32 50.36 ± 12.92 0.826 pT = 0.000
 4 weeks 48.19 ± 11.90 48.24 ± 14.11 0.990 pT*G = 0.359
 8 weeks 46.09 ± 12.14 47.04 ± 10.45 0.778 pG = 0.777
 12 weeks 44.29 ± 12.57 46.20 ± 11.41 0.591
 pa 0.003 0.005
Attack frequency (times)
 Baseline 3.76 ± 2.35 3.29 ± 1.59 0.436 pT = 0.002
 4 weeks 3.44 ± 2.18 4.95 ± 3.58 0.085 pT*G = 0.204
 8 weeks 3.00 ± 2.04 3.62 ± 3.12 0.424 pG = 0.313
 12 weeks 2.64 ± 2.89 3.29 ± 1.77 0.378
 pa 0.025 0.149
VAS score
 Baseline 6.40 ± 1.55 5.60 ± 1.57 0.095 pT = 0.000
 4 weeks 5.44 ± 1.63 4.81 ± 2.16 0.266 pT*G = 0.590
 8 weeks 4.52 ± 2.38 4.05 ± 2.06 0.480 pG = 0.346
 12 weeks 3.16 ± 2.24 3.33 ± 1.90# 0.782
 pa <0.001 <0.001
Intensity of the migraine
 Baseline 2.00 ± 0.54 2.04 ± 0.67 0.829 pT = 0.000
 4 weeks 1.43 ± 0.926 1.96 ± 0.539 0.019 pT*G = 0.144
 8 weeks 1.38 ± 0.740 1.64 ± 0.995 0.330 pG = 0.112
 12 weeks 1.38 ± 0.669 1.60 ± 0.913 0.367
 pa 0.006 0.019

Values are expressed as (Mean ± SD).SA, sham acupuncture; SAS, Zung self-rating anxiety scale; SDS, Zung self-rating depression scale; TA, true acupuncture; VAS, visual analog scale.

*The pa based on a paired-t test within-group comparisons; The pb based on t-test between the two groups; pc based on repeated measures; pT, values for comparison between different time points; pT*G based on Time*Group interaction; pG based on comparison between different groups.