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. 2021 Oct 4;9:682160. doi: 10.3389/fped.2021.682160

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Copyright © 2021 Amatya, Ye, Yang, Gandhi, Wu, Nagourney and Floros.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The two SNP interaction in RDS susceptibility. Associations between RDS and the two SNP-SNP interactions are shown. The star marks the SFTPA2 SNP shown to associate with RDS by itself. (A) depicts the two SNP-SNP intergenic and intragenic interactions of the hydrophilic SP genes associated with RDS. (B) depicts the two SNP-SNP intergenic and intragenic interactions of the hydrophobic SP genes associated with RDS.