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. 2021 Oct 4;12:730105. doi: 10.3389/fimmu.2021.730105

Table 1.

Haplotyping to support the validity of diverse 5’UTR-leader sequence of allele IGHV4-4*02 and IGHV4-4*07.

Data set IGHV gene and upstream sequence IGHJ6 read distribution
IGHJ6*02 IGHJ6*03
ERR2567266 IGHV4-4*02-C 58 0
IGHV4-4*07-A 1 107
ERR2567189 IGHV4-4*02-F 0 24
IGHV4-4*07-E 37 0
ERR2567200 IGHV4-4*02-C 0 46
IGHV4-4*07-B 48 0
ERR2567230 IGHV4-4*02-A 0 38
IGHV4-4*07-D 72 0
ERR2567192 IGHV4-4*02-C 16 0
IGHV4-4*02-A 0 17
ERR2567204 IGHV4-4*02-C 74 0
IGHV4-4*02-D 0 75
ERR2567246 IGHV4-4*02-F 0 65
IGHV4-4*02-C 36 0
ERR2567254 IGHV4-4*02-C 55 0
IGHV4-4*02-F 0 42
ERR2567261 IGHV4-4*02-C 99 0
IGHV4-4*02-F 0 78
ERR2567271 IGHV4-4*02-D 51 0
IGHV4-4*02-F 0 5
ERR2567274 IGHV4-4*02-E 24 0
IGHV4-4*02-C 0 21
ERR2567187 IGHV4-4*02-C 65 0
IGHV4-4*01
ERR2567201 IGHV4-4*07-E 27 0
IGHV4-4*07-D 0 35
ERR2567263 IGHV4-4*07-F 0 94
IGHV4-4*07-C 84 1

The sequence counts of 5’UTR-leader sequences of alleles of IGHV4-4 associated to different alleles of IGHJ6 in rearranged sequences. Haplotyping data for other 5’UTR-leader sequences are available in Supplementary Table 2 .

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