Table 1.
Characteristics of the included studies
| Reference | Year | Region (country) | Design | Setting | COVID start | COVID end | Stroke network model | Population served |
|---|---|---|---|---|---|---|---|---|
| Agarwal et al. 24 | 2020 | New York City (USA) | Retrospective a | Single center | 1 Mar 2020 | 15 May 2020 | Unknown | Unknown |
| Baracchini et al. 38 | 2020 | Veneto (Italy) | Retrospective | Single center | 1 Feb 2020 | 31 Mar 2020 | Drip&ship | Unknown |
| de Havenon et al. 16 | 2020 | USA | Retrospective | Multicenter | 1 Feb 2020 | 31 Mar 2020 | Unknown | Unknown |
| Diegoli et al. 28 | 2020 | Joinville (Brazil) | Prospective | Multicenter | 17 Mar 2020 | 15 Apr 2020 | Mothership | 590,466 |
| Esenwa et al. 39 | 2020 | New York City (USA) | Retrospective | Multicenter | 1 Jan 2020 | 25 Feb 2020 | Drip&ship | 2,000,000 |
| Hsiao et al. 40 | 2020 | Ohio, Kentucky, Indiana (USA) | Retrospective | Multicenter | 9 Mar 2020 | 12 Apr 2020 | Drip&ship | 2,100,000 |
| Huang et al. 37 | 2020 | Mayo Clinic (USA) | Retrospective | Multicenter | 11 Mar 2020 | 09 Apr 2020 | Drip&ship | Unknown |
| Jasne et al. 32 | 2020 | Connecticut (USA) | Retrospective a | Multicenter | 1 Mar 2020 | 28 Apr 2020 | Mothership b | Unknown |
| Kerleroux et al. 27 c | 2020 | France | Prospective | Multicenter national level | 15 Feb 2020 | 30 Mar 2020 | Unknown | Unknown |
| Mehrpour et al. 41 | 2020 | Iran | Retrospective | Single center | 15 Feb 2020 | 15 Apr 2020 | Drip&ship | 2,000,000 |
| Montaner et al. 29 | 2020 | Seville (Spain) | Prospective | Multicenter | Unknown | Unknown | Drip&ship | 2,450,000 |
| Naccarato et al. 6 | 2020 | Trieste (Italy) | Retrospective | Single center | 9 Mar 2020 | 09 Apr 2020 | Drip&ship | 373,803 |
| Nguyen-Huynh et al. 10 | 2020 | Northern California (USA) | Retrospective a | Multicenter | 15 Mar 2020 | 09 May 2020 | Drip&ship | 4,400,000 |
| Onteddu et al. 25 | 2020 | USA | Retrospective | TriNetX platform | 20 Jan 2020 | 16 May 2020 | Unknown | Unknown |
| Paliwal et al. 34 | 2020 | Singapore | Retrospective | Single center | 7 Feb 2020 | 30 Apr 2020 | Mothership | 1,300,000 |
| Pandey et al. 19 | 2020 | Michigan and North-West Ohio (USA) | Retrospective | Multicenter | 1 Mar 2020 | 31 Mar 2020 | Unknown | Unknown |
| Perry et al. 35 | 2020 | North Central London (UK) | Retrospective | Single center | 1 Apr 2020 | 11 May 2020 | Mothership | 1,270,000 |
| Pop et al. 36 | 2020 | Alsace (France) | Retrospective | Multicenter | 1 Mar 2020 | 31 Mar 2020 | Mothership | 1,900,000 |
| Rudilosso et al. 30 | 2020 | Barcelona (Spain) | Prospective | Single center | 1 Mar 2020 | 31 Mar 2020 | Drip&ship d | 2,740,000 |
| Saxhaug Kristoffersen et al. 23 | 2020 | Akershus University Hospital (Norway) | Retrospective, observational | Single center | 13 Mar 2020 | 30 Apr 2020 | Mothership | 570,000 |
| Schirmer et al. 31 | 2020 | USA | Retrospective a | Multicenter | 1 Mar 2020 | 28 Mar 2020 | Unknown | Unknown |
| Siegler et al. 42 | 2020 | Cooper University Hospital (NJ, USA) | Retrospective | Single center | 1 Mar 2020 | 15 Apr 2020 | Drip&ship | 2,500,000 |
| Strasser et al. 26 | 2020 | Florida (USA) | Retrospective | Single center | 1 Mar 2020 | 30 Apr 2020 | Unknown | Unknown |
| Tejada Meza et al. 5 | 2020 | Aragon (Spain) | Retrospective | Multicenter | 14 Mar 2020 | 19 Apr 2020 | Drip&ship e | 1,319,291 |
| Tejada Meza et al. 43 | 2020 | Aragon (Spain) | Retrospective | Multicenter | 09 Mar 2020 | 03 May 2020 | Drip&ship e | 11,500,000 |
| Teo et al. 22 | 2020 | Hong Kong | Retrospective | Single center | 23 Jan 2020 | 24 Mar 2020 | Mothership | 500,000 |
| Yang et al. 21 | 2020 | Beijing (China) | Prospective | Single center | 23 Jan 2020 | 07 Mar 2020 | Mothership | Unknown |
| Zhao et al. 33 c | 2020 | China | Retrospective | Multicenter (China Registry) | 01 Jan 2020 | 29 Feb 2020 | Unknown | Unknown |
| Zini et al. 4 | 2020 | Bologna (Italy) | Retrospective | Single center | 01 Mar 2020 | 30 Apr 2020 | Mothership | 1,100,000 |
a
Get-with-the-guidelines AHA study (except Aragon, mothership).
b
Network based on drip&ship, reported data only for comprehensive stroke center mothership admissions (own catchment area).
c
Endovascular treatment registry.
d
Except direct admission to comprehensive stroke center with mothership paradigm in limited central area.
e
Except Aragon (mothership).