. 2021 Oct 30;27(4):482–494. doi: 10.5056/jnm20290

Table 3.

Pathophysiological, Clinical, and Temporal Relation of Abdominal Migraine, Cyclic Vomiting Syndrome, Infantile Colic, Irritable Bowel Syndrome, and Functional Dyspepsia With Migraine

Pathology	Common physiopathology	Common clinical features	Temporal course
Abdominal migraine	Gastric motility alteration	Triggering/relieving factors	Precursor of migraine in adulthood
Abdominal migraine	Increased gut permeability	Family history of migraine	Precursor of migraine in adulthood
Cyclic vomiting syndrome	Neuronal hyperexcitation	Anxiety/depression in personal or family history	Precursor of migraine in adulthood
Cyclic vomiting syndrome	Gastric motility alteration	Anxiety/depression in personal or family history	Precursor of migraine in adulthood
Infantile colic	Microbiota modification	Anxiety/depression in personal or family history	Precursor of migraine in adulthood
Infantile colic	Increased gut inflammation and permeability	Family history of migraine	Precursor of migraine in adulthood
Irritable bowel syndrome	Visceral hyperalgesia	Amelioration of symptoms with FODMAPs exclusive regime	Co-occurrence with migraine
Irritable bowel syndrome	Increased gut permeability and immune-allergic response	Anxiety/depression in personal or family history	Co-occurrence with migraine
Functional dyspepsia	Gastric motility alteration	Anxiety/depression in personal history	Co-occurrence with migraine
	Visceral hyperalgesia
	Increased immune-allergic response

FODMAPs, fermentable oligosaccharides, disaccharides, monosaccharides, and polyols.