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. 2021 Oct 30;27(4):453–481. doi: 10.5056/jnm21077
  • Statement 19: The effectiveness of on-demand proton pump inhibitor therapy is comparable with that of continuous daily proton pump inhibitor therapy for the long-term management of patients with non-erosive reflux disease or mild erosive reflux disease.

  •      Level of evidence: moderate

  •      Strength of recommendation: weak

  •      Experts’ opinions: agree strongly (31.1%), agree with some reservations (57.8%), undecided (11.1%), disagree (0.0%), and disagree strongly (0.0%)