Table 2.
Muscle mass and function in different patients with or without acarbose
| Number | SMI (kg/m2) | p value | Handgrip strength (kg) | p value | Gait speed (m/s) | p value | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Using | Not using | Using | Not using | Using | Not using | |||||
| Classified by gender | ||||||||||
| Male | 633 | 7.46 (7.32, 7.60) | 7.67 (7.59, 7.74) | 0.042 | 29.45 (28.05, 30.85) | 31.14 (30.49, 31.79) | 0.013 | 1.22 (1.17, 1.26) | 1.30 (1.28, 1.32) | < 0.001 |
| Female | 409 | 6.11 (5.97, 6.26) | 6.31 (6.22, 6.40) | 0.019 | 17.09 (16.24, 17.93) | 19.76 (19.12, 20.41) | < 0.001 | 1.15 (1.11, 1.20) | 1.21 (1.19, 1.24) | 0.003 |
| Classified by diabetes duration | ||||||||||
| ≥ 10 years | 426 | 6.77 (6.60, 6.94) | 6.93 (6.81, 7.06) | 0.119 | 22.82 (21.41, 24.23) | 24.38 (23.35, 25.42) | 0.067 | 1.16 (1.13, 1.20) | 1.22 (1.19, 1.25) | 0.002 |
| < 10 years | 616 | 6.88 (6.65, 7.11) | 7.29 (7.20, 7.38) | 0.002 | 24.63 (22.52, 26.74) | 28.28 (27.56, 29.00) | 0.001 | 1.23 (1.17, 1.29) | 1.29 (1.27, 1.31) | 0.055 |
| Classified by BMI | ||||||||||
| BMI ≥ 25 kg/m2 | 471 | 7.38 (7.19, 7.57) | 7.74 (7.64, 7.83) | 0.004 | 24.51 (22.45, 26.57) | 28.10 (27.22, 28.99) | 0.001 | 1.19 (1.15, 1.24) | 1.27 (1.24, 1.29) | 0.004 |
| BMI < 25 kg/m2 | 571 | 6.41 (6.26, 6.56) | 6.67 (6.59, 6.76) | 0.002 | 22.65 (21.27, 24.04) | 25.97 (25.15, 26.79) | < 0.001 | 1.18 (1.14, 1.22) | 1.27 (1.25, 1.29) | < 0.001 |
| Classified by HbA1c | ||||||||||
| HbA1c ≥ 9% | 482 | 6.67 (6.46, 6.87) | 7.19 (7.08, 7.29) | < 0.001 | 21.68 (19.83, 23.52) | 26.64 (25.78, 27.49) | < 0.001 | 1.13 (1.08, 1.18) | 1.26 (1.24, 1.28) | < 0.001 |
| HbA1c < 9% | 505 | 6.90 (6.72, 7.08) | 7.13 (7.02, 7.23) | 0.046 | 24.39 (22.86, 25.92) | 27.13 (26.22, 28.04) | 0.003 | 1.21 (1.17, 1.25) | 1.27 (1.25, 1.29) | 0.005 |
BMI body mass index, SMI skeletal muscle index