Figure 8.

Discovery and identification of novel Nucleotide Motifs located in central regions of the Promoter Regions using MEME-ChIP (v5.3.3). The Motifs were discovered and identified by importing a 500bp-length sequence surrounding the summit of MACS peaks into the MEME-ChIP program (v5.3.3). The motifs were then compared against HOCOMOCO v11 Database using Tomtom-Motif Comparison Tool to identify similar known motifs and Top 3 hits with E-value < 0.05 were (a) HOXC10, (b) CPEB1, and (c) PRDM6.