Table 5.
Diagnostic Yield of Different Laboratory Tests on Induced Sputum and Stool Specimens Among Bacteriologically Confirmed Pulmonary Tuberculosis (PTB) by Induced Sputum, Among All Children (< 15 Years of Age) With Diagnosed PTB and All Children (< 15 Years of Age) With Presumptive PTB Enrolled From Selected 4 Tertiary Care Hospitals in Dhaka, Bangladesh, January 2018–April 2019 (N = 447)
| Investigations | No. | Percentage Against: | ||
|---|---|---|---|---|
| Bacteriologically Confirmeda (n = 72) | Total Diagnoseda (n = 111) | Presumptive PTBa (n = 447) | ||
| Only culture on IS | 9 | 12.5 | 8.1 | 2.0 |
| Only Xpert on IS | 12 | 16.7 | 10.8 | 2.7 |
| Only Xpert Ultra on IS | 28 | 38.9 | 25.2 | 6.3 |
| Culture plus Xpert on IS | 13 | 18.1 | 11.7 | 2.9 |
| Culture plus Xpert Ultra on IS | 29 | 40.3 | 26.1 | 6.5 |
| Only Xpert on stool specimen | 11 | 15.3 | 9.9 | 2.5 |
| Only Xpert Ultra on stool specimen | 60 | 83.3 | 54.1 | 13.4 |
| Only Xpert Ultra on stool specimen with trace as negative | 12 | 16.7 | 10.8 | 2.7 |
| Xpert on IS plus Xpert on stool specimen | 14 | 19.4 | 12.6 | 3.1 |
| Xpert on IS plus Xpert Ultra on stool specimen | 62 | 86.1 | 55.9 | 13.9 |
| Xpert Ultra on IS plus Xpert Ultra on stool specimen | 71 | 98.6 | 64.0 | 15.9 |
| Xpert on IS plus Xpert Ultra on stool specimen with trace as negative | 17 | 23.6 | 15.3 | 3.8 |
| Xpert Ultra assay on IS plus Xpert Ultra on stool specimen with trace as negative | 29 | 40.3 | 26.1 | 6.5 |
Abbreviations: IS, induced sputum; PTB, pulmonary tuberculosis.
aEither on induced sputum or stool.