Table 1.
Summary of study and population characteristics for studies included in the meta-analysis.
| Author, year | Country | Ethnicity | Cases | Controls | Case genotype |
Control genotype |
Case genotype |
Control genotype |
HWE P | NOS Score | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Arg | His | Arg | His | Arg/Arg | Arg/His | His/His | Arg/Arg | Arg/His | His/His | |||||||
| Tranah, 2004 17 | USA | Caucasian | 376 | 725 | 656 (87) | 96 (13) | 1270 (88) | 180 (12) | 302 | 52 | 22 | 582 | 106 | 37 | 0.12 | 6 |
| Moreno, 2006 18 | Italy | Caucasian | 350 | 316 | 631 (90) | 69 (10) | 575 (91) | 57 (9) | 287 | 57 | 6 | 265 | 45 | 6 | 0.02 | 6 |
| Curtin, 2009 19 | USA | Caucasian | 1209 | 1380 | 2213 (92) | 205 (8) | 2538 (92) | 222 (8) | 1014 | 185 | 10 | 1167 | 204 | 9 | 0.98 | 7 |
| Krupa, 2011 20 | Poland | Caucasian | 100 | 100 | 168 (84) | 32 (16) | 182 (91) | 18 (9) | 75 | 18 | 7 | 84 | 14 | 2 | 0.14 | 8 |
| Cetinkunar, 2015 21 | Turkey | Asian | 71 | 86 | 94 (66) | 48 (34) | 129 (75) | 43 (25) | 32 | 30 | 9 | 54 | 21 | 11 | 0.00 | 6 |
| Balkan, 2020 22 | Turkey | Asian | 40 | 40 | 76 (95) | 4 (5) | 70 (88) | 10 (12) | 36 | 4 | 0 | 30 | 10 | 0 | 0.36 | 6 |
| Hridy, 2020 23 | Bangladesh | Asian | 185 | 183 | 233 (63) | 137 (37) | 254 (69) | 112 (31) | 63 | 107 | 15 | 83 | 88 | 12 | 0.07 | 7 |
Data presented as n or n (%) prevalence.
Arg, arginine; His, histidine; HWE, Hardy–Weinberg equilibrium; NOS, Newcastle-Ottawa quality assessment scale.