Table 2.
Change in CAT, SABA use and adherence over 6 months using linear mixed effects models.
|
Mean (SD) at
baseline |
Mean (SD) at
6 months |
Estimates* | Lower 95% CI* | Upper 95% CI* | P-value | |
|---|---|---|---|---|---|---|
| Overall, n = 611 | ||||||
| CAT | 22.6 (7.8) | 21.7 (8.1) | −0.9 | −1.4 | −0.4 | p <0.001 |
| SABA use, puffs/day | 2.3 (3.1) | 1.6 (2.5) | −0.6 | −0.8 | −0.4 | p < 0.001 |
| Adherence, % | 81.1 (27.1) | 76.8 (29.8) | −4.0 | −6.9 | −1.2 | p = 0.01 |
| High burden, n = 378 | ||||||
| CAT | 27.4 (4.7) | 25.4 (6.6) | −2.0 | −2.6 | −1.4 | p < 0.001 |
| SABA use, puffs/day | 2.7 (3.4) | 1.8 (2.5) | −0.8 | −1.1 | −0.6 | p < 0.001 |
| Adherence, % | 79.6 (27.0) | 74.5 (30.3) | −4.6 | −8.4 | −0.9 | p = 0.01 |
| Low burden, n = 233 | ||||||
| CAT | 14.7 (4.8) | 15.6 (6.5) | 0.9 | 0.1 | 1.7 | p = 0.03 |
| SABA use, puffs/day | 1.7 (2.4) | 1.3 (2.3) | −0.3 | −0.6 | −0.1 | p = 0.01 |
| Adherence, % | 82.8 (27.2) | 80.0 (28.8) | −3.5 | −8.2 | 1.2 | p = 0.14 |
*
Adjusted for enrollment month.