Table 5.
Index test 4AT (cutoff ≥4) against reference standard DSM-IV-TR criteria (OBS scale and patient records), indeterminate diagnosis excluded, n = 195
| Comparisons | True pos. | True neg. | False pos. | False neg. | OPA % | Sensitivity (95% CI) | Specificity(95% CI) | PPV(95% CI) | NPV(95% CI) | Youden’s Index | AUROC(95% CI) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total sample (n = 195) | 23 | 149 | 13 | 10 | 88% | 0.70 (0.51–0.84) | 0.92 (0.87–0.96) | 0.64 (0.50–0.76) | 0.94 (0.90–0.96) | 0.617 | 0.808 (0.746–0.861) |
| University hospital (n = 95) | 12 | 71 | 6 | 6 | 87% | 0.67 (0.41–0.87) | 0.92 (0.84–0.97) | 0.67 (0.47–0.82) | 0.92 (0.86–0.96) | 0.589 | 0.794 (0.699–0.870) |
| County hospital (n = 100) | 11 | 78 | 7 | 4 | 89% | 0.73 (0.45–0.92) | 0.92 (0.84–0.97) | 0.61 (0.42–0.77) | 0.95 (0.89–0.98) | 0.651 | 0.825 (0.737–0.894) |
| University hospital, special warda (n = 63) | 10 | 42 | 5 | 6 | 82% | 0.63 (0.35–0.85) | 0.89 (0.77–0.96) | 0.67 (0.45–0.83) | 0.88 (0.79–0.93) | 0.519 | 0.759 (0.635–0.858) |
| University hospital, general wardsb (n = 32) | 2 | 29 | 1 | 0 | 97% | 1.00 (0.16–1.00) | 0.97 (0.83–1.00) | 0.67 (0.23–0.93) | 1.00n.a. | 0.967 | 0.983 (0.861–1.00) |
| Both hospitals, general wardsc (n = 132) | 13 | 107 | 8 | 4 | 91% | 0–77 (0.50–0.93) | 0.93 (0.87–0.97) | 0.62 (0.44–0.77) | 0.96 (0.92–0.98) | 0.695 | 0.848 (0.775–0.904) |
| Patients with dementia (n = 50) | 11 | 30 | 6 | 3 | 82% | 0.79 (0.49–0.95) | 0.83 (0.67–0.94) | 0.65 (0.46–0.80) | 0.91 (0.78–0.97) | 0.619 | 0.810 (0.674–0.907) |
| Patients without dementia (n = 145) | 12 | 119 | 7 | 7 | 90% | 0.63 (0.38–0.84) | 0.94 (0.89–0.98) | 0.63 (0.44–0.79) | 0.94 (0.90–0.97) | 0.575 | 0.788 (0.712–0.851) |
n.a. not applicable due to small numbers
aSevere cognitive impairment
bGeriatric stroke/neurology, geriatric multi-morbidity
c Orthopedics, urology, geriatric stroke/neurology, geriatric multi-morbidity