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. 2021 Oct 18;16:612. doi: 10.1186/s13018-021-02714-w

Table 2.

The association between total testosterone (ng/dL) and total bone mineral density (g/cm2)

Model 1 Model 2 Model 3
β (95% CI) P value β (95% CI) P value β (95% CI) P value
Total testosterone (ng/dL) 0.0001 (0.0001, 0.0001)  < 0.000001 0.0000 (− 0.0000, 0.0000) 0.907372 0.0001 (0.0001, 0.0002)  < 0.000001
Total testosterone categories
 Q1 0 0 0
 Q2 0.0067 (− 0.0026, 0.0160) 0.159252 0.0034 (− 0.0055, 0.0123) 0.449622 0.0057 (− 0.0035, 0.0150) 0.223303
 Q3 0.0633 (− 0.0540, 0.0726) < 0.000001 0.0023 (− 0.0171, 0.0217) 0.815594 0.0044 (− 0.0154, 0.0242) 0.665964
 Q4 0.0775 (0.0682, 0.0867) < 0.000001 0.0104 (− 0.0108, 0.0315) 0.335823 0.0155 (− 0.0063, 0.0372) 0.162864
Subgroup analysis stratified by sex
 Men 0.0000 (− 0.0000, 0.0000) 0.719289 0.0000 (− 0.0000, 0.0000) 0.864406 0.0000 (− 0.0000, 0.0000) 0.36741
 Women − 0.0001 (− 0.0002, 0.0001) 0.492458 − 0.0001 (− 0.0002, 0.0001) 0.270182 − 0.0001 (− 0.0003, 0.0000) 0.151631
Subgroup analysis stratified by race/ethnicity
 Non-Hispanic white 0.0001 (0.0001, 0.0001) < 0.000001 − 0.0001 (− 0.0001, 0.0000) 0.062793 − 0.0001 (− 0.0001, 0.0000) 0.324209
 Non-Hispanic black 0.0001 (0.0001, 0.0002) < 0.000001 0.0000 (− 0.0000, 0.0001) 0.521033 0.0000 (− 0.0000, 0.0001) 0.303087
 Mexican American 0.0001 (0.0001, 0.0001) < 0.000001 − 0.0001 (− 0.0001, 0.0000) 0.05225 − 0.0000 (− 0.0001, 0.0000) 0.155034
 Other race/ethnicity 0.0001 (0.0001, 0.0002) < 0.000001 0.0000 (− 0.0000, 0.0001) 0.193526 0.0000 (− 0.0000, 0.0001) 0.315806

Model 1: no covariates were adjusted. Model 2: age, sex, and race/ethnicity were adjusted. Model 3: age, sex, race/ethnicity, education, income poverty ratio, total protein, serum phosphorus and serum calcium were adjusted. In the subgroup analysis stratified by sex and race/ethnicity, the model is not adjusted for sex and race/ethnicity, respectively