Table 1.

Resolution of pulmonary hypertension

	Any Pulmonary Hypertension (n = 143)	Resolution after 1 yr of Age (n = 25)	Resolution before 1 yr of Age (n = 118)	P Value
Sex, % female	46.9	52.0	45.8	0.57
Race/ethnicity, % non-White	69.2	60.0	71.2	0.27
Gestational age, mean ± SD (range), wk	26.0 ± 2.2 (23–32)	26.8 ± 2.9 (23–32)	25.9 ± 2.0 (23–30.7)	0.07
Birthweight, mean ± SD (range), grams	815 ± 295 (380–1,900)	957 ± 447 (420–1,900)	785 ± 243 (380–1,650)	0.008
Birthweight percentile, mean ± SD (range), %	40 ± 24 (1–94)	36 ± 23 (2–88)	41 ± 24 (1–94)	0.37
G-tube, % yes	55.9	92.0	48.3	<0.001
Nissen fundoplication, % yes	37.8	72.0	30.5	<0.001
Supplemental oxygen at discharge, % yes	65.0	72.0	63.6	0.42
Initial oxygen amount, mean ± SD (range), LPM	0.53 ± 0.43 (0.13–2.00) (n = 93)	0.94 ± 0.59 (0.13–2.00) (n = 18)	0.43 ± 0.31 (0.13–1.50) (n = 75)	<0.001
Age at home oxygen discontinuation, median (95% CI), yr	1.18 (1.12–1.34) (n = 93)	1.97 (1.59–3.95) (n = 18)	1.13 (1.02–1.18) (n = 75)	<0.001*
Diuretics, % yes	79.0	96.0	75.4	0.022
Tracheostomy, % yes	11.9	32.0	7.6	0.001
Home ventilator, % yes	10.5	32.0	5.9	<0.001
PDA requiring procedure, % yes	38.5	48.0	36.4	0.28
CSF shunt, % yes	10.5	20.0	8.5	0.09
Initial length of stay, mean ± SD (range), d	195 ± 125 (53–806)	296 ± 189 (92–806)	173 ± 95 (53–744)	<0.001
Outpatient vasodilator therapy, % yes†	24.5	44.0	20.3	0.012

Definition of abbreviations: CI = confidence interval; CSF = cerebrospinal fluid; LPM = liters per minute; PDA = patent ductus arteriosus; SD = standard deviation.

^*P value generated via Wilcoxon rank-sum test.

^†Out of the 143 subjects, 30 subjects were on sildenafil alone, 4 were on sildenafil and bosentan, and 1 was on sildenafil and treprostinil.