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. 2021 Oct 4;68(1):204–213. doi: 10.1093/clinchem/hvab216

Table 1.

Demographics, comorbidities, and plasma SARS-CoV-2 nucleocapsid antigen concentrations for individuals with plasma samples drawn ±1 day from diagnostic respiratory NAAT (n = 74).

Covariatea Overall (n = 74) Outpatient (n = 18) Inpatientb (n = 30) ICU (n = 26) P valuec
Age, years 56 (37–75) 43 (31–63) 60 (39–82) 61 (40–72) 0.07
Sex (female) 39 (52.7) 10 (55.6) 19 (63.3) 10 (38.5) 0.2
Diabetes 27 (36.5) 4 (22.2) 10 (33.3) 13 (50.0) 0.1
Hypertension 31 (41.9) 5 (27.8) 11 (36.7) 15 (57.7) 0.1
Obesity 31 (41.9) 6 (33.3) 13 (43.3) 12 (46.2) 0.7
Days Sxd 7 (3–10) 7 (4–10) 5 (2–10) 8 (3–11) 0.3
Resp. Cte 25.8 (18.6–30.9) 28.4 (16.3–33.2) 25.8 (18.7–31.1) 23.4 (19.1–29.4) 0.6
Log10 Agf 6.2 (5.4–6.7) 5.4 (3.9–6.0) 6.0 (5.4–6.5) 6.6 (6.1–7.2) <0.001
a

Continuous variables reported as median (interquartile range); categorical variables reported as N (%).

b

Inpatients excluding those requiring intensive care.

c

Kruskal-Wallis test.

d

Days from symptom onset.

e

Respiratory NAAT Ct.

f

Log10 Ag, Log10 nucleocapsid antigen concentration (fg/mL).