Table 1.
Demographic Variables and Medical History by Disease Severitya
| Demographic and Medical History | Severe (n = 352) |
Critical Without IMV (n = 414) |
Critical With IMV (n = 334) |
MSOD (n = 262) |
|---|---|---|---|---|
| Demographic | ||||
| Sex | ||||
| Female | 131 (37.2) | 129 (31.2) | 101 (30.2) | 94 (35.9) |
| Male | 221 (62.8) | 285 (68.8) | 233 (69.8) | 168 (64.1) |
| Age, years (SD) | 60.5 (14.8) | 60.5 (14.5) | 58.1 (14.3) | 60.1 (13.2) |
| BMI, kg/m2 (SD) | 31.5 (7.7) | 31.3 (7.4) | 31.9 (7.8) | 33.2 (10.5) |
| Ethnicity, Hispanic or Latino | 66 (18.8) | 130 (31.4) | 109 (32.6) | 73 (27.9) |
| Race | ||||
| American Indian or Alaska Native | 2 (0.6) | 2 (0.5) | 1 (0.3) | 1 (0.4) |
| Asian | 29 (8.2) | 20 (4.8) | 21 (6.3) | 17 (6.5) |
| Black or African American | 72 (20.5) | 75 (18.1) | 56 (16.8) | 57 (21.8) |
| Native Hawaiian or Other Pacific Islander | 4 (1.1) | 1 (0.2) | 0 (0) | 0 (0) |
| White | 141 (40.1) | 144 (34.8) | 136 (40.7) | 70 (26.7) |
| Other | 41 (11.6) | 64 (15.5) | 34 (10.2) | 30 (11.5) |
| Not reported | 63 (17.9) | 108 (26.1) | 86 (25.7) | 87 (33.2) |
| Medical History | ||||
| Days between diagnosis and study enrollment (IQR) | 3 (1–5) | 3 (1–6) | 4 (2–7) | 4 (2–7) |
| Duration of pneumonia before enrollment, days (IQR) | 8 (4–11) | 9 (5–12) | 8 (5–12) | 8 (5–12) |
| Duration of hospitalization before enrollment (days) (IQR) | 3 (2–5) | 4 (3–6) | 5 (3–8) | 5 (3–8) |
| Number of patients admitted to ICU before enrollment | 15 (4.3) | 30 (7.2) | 107 (32.0) | 80 (30.5) |
| Fever | 152 (43.2) | 164 (39.6) | 202 (60.5) | 149 (56.9) |
| Obesity | 164 (46.6) | 184 (44.4) | 163 (48.8) | 134 (51.1) |
| Hypertension | 182 (51.7) | 219 (52.9) | 147 (44.0) | 145 (55.3) |
| Diabetes | 70 (19.9) | 77 (18.6) | 57 (17.1) | 60 (22.9) |
| Corticosteroid use | 74 (21.0) | 147 (35.5) | 78 (23.4) | 67 (25.6) |
| Vasopressor use | 13 (3.7) | 6 (1.4) | 90 (26.9) | 180 (68.7) |
| Immunocompromised | 10 (2.8) | 6 (1.4) | 12 (3.5) | 11 (4.2) |
Abbreviations: BMI, body mass index; ICU, intensive care unit; IMV, invasive mechanical ventilation; IQR, interquartile range; MSOD, multisystem organ dysfunction; SD, standard deviation.
aData are presented as n (%), mean (SD), or median (Q1–Q3). Demographic and medical history information from patients included in the analysis.